By Paul R. Ortiz de Montellano
This authoritative Fourth variation summarizes the advances of the earlier decade in regards to the constitution, mechanism, and biochemistry of cytochrome P450 enzymes, with adequate assurance of previous paintings to make every one bankruptcy a accomplished evaluation of the sector. 13 chapters are divided into targeted volumes, the 1st masking the basics of cytochrome P450 biochemistry, in addition to the microbial, plant, and bug structures, and the second one solely targeting mammalian systems.
Volume 1 starts off with an exploration of the biophysics and mechanistic enzymology of cytochrome P450 enzymes, with a dialogue of the constructions of P450 enzymes and their electron donor companions, the mechanisms of oxygen activation and substrate oxidation, and the methods and nature of cytochrome P450 inhibition. extra chapters talk about the character and roles of cytochrome P450 enzymes in microbes, crops and bugs, and an 8th bankruptcy is a survey of the capability application of P450 enzymes in biotechnology. the 1st bankruptcy of quantity 2 examines the jobs of P450 enzymes in mammals, commonly people. 4 additional chapters then care for the genetic and hormonal legislation of P450 enzymes and their particular roles within the processing of sterols and lipids. Cytochrome P450: constitution, Mechanism, and Biochemistry is a key source for scientists, professors, and scholars attracted to fields as various as biochemistry, chemistry, biophysics, molecular biology, pharmacology and toxicology.
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Additional resources for Cytochrome P450: Structure, Mechanism, and Biochemistry
Cytochrome P450: Structure, Mechanism, and Biochemistry by Paul R. Ortiz de Montellano