Read e-book online Biochemistry of Platelets PDF

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By David Phillips

Biochemistry of Platelets is a entire overview of the biochemistry of platelets, with emphasis at the molecular foundation for some of the organic methods during which they take part. issues diversity from stimulus-response coupling mechanisms to platelet contractile proteins, platelet membrane glycoproteins, and garage organelles in platelets and megakaryocytes. The expression and serve as of adhesive proteins at the platelet floor is additionally discussed.

Comprised of 12 chapters, this booklet starts with an outline of the morphological and metabolic responses to agonists, in addition to the involvement of definite techniques within the coupling of agonist-receptor interactions to platelet responses. the next bankruptcy offers with platelet arachidonate metabolism and platelet-activating issue, concentrating on the discharge of arachidonate from platelet lipid shops; pathways of platelet arachidonate metabolism and results of arachidonate metabolites; and inhibition of platelet arachidonate metabolism by way of aspirin. The constitution, functionality, and amendment in illness of platelet membrane glycoproteins are then mentioned, in addition to prothrombin activation on platelets and platelet rules of thrombus formation. Secreted platelet proteins as markers for pathological problems also are considered.

This monograph is meant as a reference for investigators excited by platelet examine in addition to a resource of knowledge for these operating in different parts of organic investigation.

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Biochemistry of Platelets by David Phillips

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