Errol C Friedberg's A Biography of Paul Berg:The Recombinant DNA Controversy PDF

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By Errol C Friedberg

With a Foreword by way of Sydney Brenner (Nobel laureate in body structure or medication, 2002)

This biography information the lifetime of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's lifestyles from delivery, in 1926, to the current, with unique emphasis on his huge, immense medical contributions, together with being the 1st to improve expertise that ended in gene cloning technology. In 1980, Berg bought a Nobel Prize in chemistry for this work.

In addition to his contributions within the learn laboratory, Berg orchestrated and oversaw a ancient assembly at Asilomar, California that established on a threatening controversy surrounding the conception via a few of the destructive capability of recombinant DNA know-how. This assembly did a lot to stop this controversy and to install position the legislation of recombinant DNA paintings, therefore placing fears to rest.

The recombinant DNA controversy used to be a historical consequence of the invention of gene cloning. significantly, it represented a paramount instance of clinical foresight and due diligence by way of the medical neighborhood, instead of through regulatory entities within the usa and lots of different nations. the last word attractiveness of gene/DNA cloning ended in a brand new period of recent biology that flourishes to the present.

This e-book is aimed basically at scientists and people in education. The ebook strives to easily supply details for the overall reader, yet isn't really particularly adapted for a basic studying audience.

While many books disguise the recombinant DNA controversy, none have satisfactorily addressed this ancient interval and are frequently contradictory concerning the many who is, where's, and why's concerned. also, the good majority of those have been written via non-scientists. This biography of Paul Berg presents entry to varied archived letters and records at Stanford college no longer formerly addressed, and to the chronology of occasions as recalled and documented by means of him, in addition to different key personalities, a lot of whom have been interviewed.

Contents:

  • Part I:
    • Growing Up in Brooklyn
    • The crucial Paul Berg
    • College — and international conflict II
    • Western Reserve University
    • Copenhagen
  • Part II:
    • Washington college, St. Louis
    • Discovering move RNA
    • Stanford collage — and Its Refurbished division of Biochemistry
    • Transcription and Translation: New Directions
  • Part III:
    • Making Recombinant DNA — the 1st Faltering Steps
    • Making Recombinant DNA — an immense Breakthrough
    • EcoRI restrict Endonuclease — an enormous Breakthrough
    • “Coincidence is the observe We Use once we cannot See the Levers and Pulleys”
    • Yet one other Stanford Contribution
  • Part IV:
    • An old assembly in Hawaii
    • The Recombinant DNA Controversy
    • A Momentous Gordon examine Conference
    • Making Recombinant Molecules with Frog DNA
    • The Controversy Heats Up
    • Asilomar II
    • The Dissenters: a distinct aspect of View
    • The Aftermath
    • Legislative and Revisionist demanding situations to Recombinant DNA
    • Asilomar II — classes Learned
  • Part V:
    • The Nobel Prize in Chemistry
    • Commercializing the Technology
    • Life is going on
    • The “Retirement” Years
    • Public coverage concerns — and different Interests
    • Personal Challenges

Readership: Researchers, graduate scholars, undergraduates in existence sciences, drugs and chemistry and lay public.

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A Biography of Paul Berg:The Recombinant DNA Controversy Revisited by Errol C Friedberg


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